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Evaluation of the harmonic scalpel in open surgery for abdominal aortic aneurysm
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《医学前沿(英文)》 2012年 第6卷 第1期 页码 85-88 doi: 10.1007/s11684-012-0174-x
The harmonic scalpel is a hemostatic device primarily designed for use in laparoscopic surgery. During the last few years, many surgeons have begun to use the harmonic scalpel in open surgery. Several papers have cited the benefits of the device compared with conventional knot-tying techniques; however, no evidence showing the advantages of using the harmonic scalpel in complicated abdominal aortic aneurysm (AAA) surgery has been presented. The aim of the present study is to determine the value of the harmonic scalpel in open operation for AAA. A total of 153 patients who underwent open surgery for AAA at the Department of Vascular Surgery of Guangdong General Hospital, China between January 2001 and December 2010, were retrospectively analyzed. Open surgery performed with the harmonic scalpel on 105 patients was compared with open operation using conventional knot-tying techniques on 48 patients. The operative time, intraoperative blood loss, total postoperative drainage fluid volumes, hospital stay, and postoperative complications between the two groups were compared. The harmonic scalpel group was associated with a shorter operation time (113.2±23.6 min vs. 232.1±39.2 min, P<0.01) and lower intraoperative blood loss (126.1±96.6 ml vs. 592.1±207.2 ml, P<0.01). Postoperative drainage fluid volumes were greater in the conventional surgery group than in the harmonic scalpel group (702.1±192.8 ml vs. 198.5±97.4 ml, P<0.01). The hospital stay was shorter for the harmonic scalpel group than for the conventional surgery group (10.7±3.3 d vs. 16.5±4.7 d, P<0.05). No differences between the postoperative complications or hospital mortality of the two groups were found. The harmonic scalpel is a safe and minimally invasive tool in open surgery for AAA and is associated with shorter operative time, shorter hospital stay, and lower intraoperative blood loss and postoperative drainage fluid volumes compared with conventional knot-tying techniques.
关键词: abdominal aortic aneurysm harmonic scalpel minimally invasive
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《医学前沿(英文)》 2017年 第11卷 第1期 页码 62-67 doi: 10.1007/s11684-017-0498-7
Chronic disseminated intravascular coagulation (DIC) is a rare but devastating complication of aortic aneurysm (AA). This study investigated the clinical manifestations, laboratory findings, and treatment of patients with AA-associated chronic DIC (AA-DIC) and explored the mechanisms, duration, and therapeutic response of AA-DIC. We retrospectively reviewed the medical records of 235 AA patients admitted at the Peking Union Medical College Hospital between September 2009 and January 2015. The patients were classified as those with DIC (AA-DIC) and those without DIC (non-DIC). The AA-DIC group showed a significantly higher proportion of female patients and a significantly longer AA disease course than the non-DIC group did. The AA-DIC patients presented mural thrombi, dissecting aneurysms, a family history of AA, and diabetes significantly more frequently than the non-DIC patients did. Furthermore, multiple regression analyses revealed that sex, mural thrombus, aneurysm type, diabetes, and stent surgery are possible independent risk factors for AA-DIC patients. Fifty-two (22.1%) patients presented AA-DIC. Among these patients, 43 had non-typical DIC and 9 had typical DIC; the mortality rate of the latter was 22.2%. The mean age of the patients with typical DIC was significantly higher than of that of patients with non-typical DIC. The non-typical DIC patients also presented abnormal coagulation disorders of varying degrees. Furthermore, heparin or low-molecular-weight heparin improved the clinical symptoms and laboratory parameters in patients with AA and typical DIC. Thus, chronic DIC should be considered in patients with AA.
关键词: aortic aneurysm disseminated intravascular coagulation anticoagulation therapy
The evolution of surgical and medical treatment of aortic root aneurysm
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《医学前沿(英文)》 2014年 第8卷 第4期 页码 427-432 doi: 10.1007/s11684-014-0385-4
Since first report of aortic root replacement in 1968, the surgical risk and long term outcome of patients with aortic root aneurysm have been continuously improving. In the last 30 years, the surgical approach is also evolving towards more valve conservation with prophylactical intervention at an earlier clinical stage. Translational research has also led to emerging surgical innovation and new drug therapy. Their efficacies are currently under vigorous clinical trials and evaluations.
关键词: aortic root aneurysm aortic root replacement valve sparing root replacement personalised external aortic root support
Xianlong MENG, Wenyu FU, Yun ZHANG, Aike QIAO,
《机械工程前沿(英文)》 2010年 第5卷 第3期 页码 328-335 doi: 10.1007/s11465-010-0026-9
关键词: reverse engineering aortic arch aneurysm surface model meshing finite element model
《医学前沿(英文)》 2021年 第15卷 第3期 页码 438-447 doi: 10.1007/s11684-020-0826-1
关键词: sporadic thoracic aortic dissection exome sequencing gene COL3A1 case–control study extracellular matrix
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《医学前沿(英文)》 2014年 第8卷 第4期 页码 419-426 doi: 10.1007/s11684-014-0383-6
Aneurysmal dilatation of the aortic sinuses of Valsalva has been most extensively documented in the setting of aortopathies, particularly Marfan syndrome. On the other hand, there is limited data in the literature about congenital sinus of Valsalva aneurysms outside this context. For the purpose of this review, we carried out a literature search on aneurysmal dilatation of the sinuses of Valsalva in Marfan syndrome, and compared this with congenital sinus of Valsalva aneurysms, also including data from a case series from our institution. In conclusion, there are differences in management of aortic dilatation in Marfan syndrome and congenital sinus of Valsalva aneurysms. Though less well-recognised, congenital aneurysms are often associated with significant morbidity and mortality and timely intervention is necessary.
关键词: sinus of Valsalva aneurysms Marfan syndrome aortic dissection
Right coronary occlusion following transcatheter aortic valve implantation: two case reports
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《医学前沿(英文)》 2016年 第10卷 第3期 页码 351-355 doi: 10.1007/s11684-016-0465-8
This paper discusses two male patients with severe aortic stenosis, whose right coronary arteries (RCA) were completely occluded during transcatheter aortic valve implantation (TAVI), leading to fatal hemodynamic disorder. Occlusions of RCA complicated by TAVI are rare. In addition, emergency cardiopulmonary bypass (CPB) played a critical role in rescuing our second patient. Both patients were admitted for “severe aortic stenosis,” and TAVIs were performed. The first patient’s blood pressure immediately dropped to 70/40 mmHg after the balloon expansion and did not increase much after the administration of aramine or fluid therapy. He did not receive emergency surgery and died after 1.5 h of resuscitation. The second patient’s blood pressure fluctuated greatly for several minutes after the valve implantation, ranging from 170/100 mmHg to 60/40 mmHg. Angiography revealed a total occlusion of RCA. Thoracic surgery with CPB was performed, and the patient survived.
关键词: aortic stenosis transcatheter aortic valve implantation right coronary occlusion cardiac group
Clinical significance of para-aortic lymph node dissection and prognosis in ovarian cancer
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《医学前沿(英文)》 2014年 第8卷 第1期 页码 96-100 doi: 10.1007/s11684-014-0316-4
Lymph node metastasis has an important effect on prognosis of patients with ovarian cancer. Moreover, the impact of para-aortic lymph node (PAN) removal on patient prognosis is still unclear. In this study, 80 patients were divided into groups A and B. Group A consisted of 30 patients who underwent PAN+ pelvic lymph node (PLN) dissection, whereas group B consisted of 50 patients who only underwent PLN dissection. Analysis of the correlation between PAN clearance and prognosis in epithelial ovarian cancer was conducted. Nineteen cases of lymph node metastasis were found in group A, among whom seven cases were positive for PAN, three cases for PLN, and nine cases for both PAN and PLN. In group B, 13 cases were positive for lymph node metastasis. Our study suggested that the metastatic rate of lymph node is 40.0%. Lymph node metastasis was significantly correlated with FIGO stage, tumor differentiation, and histological type both in groups A and B (P<0.05). In groups A and B, the three-year survival rates were 77.9% and 69.0%, and the five-year survival rates were 46.7% and 39.2%, respectively. However, the difference was not statistically significant (P>0.05). The three-year survival rates of PLN metastasis in groups A and B were 68.5% and 41.4%, and the five-year survival rates were 49.7% and 26.4%, respectively. Furthermore, PLN-positive patients who cleared PAN had significantly higher survival rate (P=0.044). In group A, the three-year survival rates of positive and negative lymph nodes were 43.5% and 72.7%, and the five-year survival rates were 27.2% and 58.5%, respectively. The difference was statistically significant (P=0.048). Cox model analysis of single factor suggested that lymph node status affected the survival rate (P<0.01), which was the death risk factor. Consequently, in ovarian carcinoma cytoreductive surgery, resection of the para-aortic lymph node, which has an important function in clinical treatment and prognosis of patients with ovarian cancer, is necessary.
关键词: ovarian cancer para-aortic lymph node pelvic lymph node
《医学前沿(英文)》 2021年 第15卷 第3期 页码 416-437 doi: 10.1007/s11684-021-0852-7
关键词: surgical aortic valve replacement trans-catheter aortic valve implantation left ventricular hypertrophy and fibrosis myocardial force-velocity relationship His-Purkinje pacing renin-angiotensin system inhibitors coronary access impairment
SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei
《医学前沿(英文)》 2007年 第1卷 第2期 页码 167-172 doi: 10.1007/s11684-007-0031-5
申颖,戴姝艳
《中国工程科学》 2015年 第17卷 第6期 页码 61-64
目的:探讨继发性中晚期腹腔妊娠的诊断以及治疗方案。方法:回顾性地分析和总结我院收治的1例继发性中晚期腹腔妊娠的诊断及治疗方案。结果:该病例经磁共振成像(MRI)检查明确诊断,同时成功予以手术治疗。结论:继发性中晚期腹腔妊娠非常罕见,临床症状不典型,早期诊断较困难,MRI是一种有效的诊断方法,手术是最重要的治疗方式。
Histopathological study of congenital aortic valve malformations in 32 children
HUANG Ping, WANG Hongwei, LI Yanping, CHENG Peixuan, LIU Qingjun, ZHANG Zhenlu, LIU Jianying
《医学前沿(英文)》 2007年 第1卷 第1期 页码 74-78 doi: 10.1007/s11684-007-0015-5
Wen YAN MD, Min FENG MD, Pei-Hua WANG MD, Dao-Wen WANG MD,
《医学前沿(英文)》 2010年 第4卷 第2期 页码 225-228 doi: 10.1007/s11684-010-0003-z
关键词: bradykinin vascular smooth muscle cells signal transduction pathways
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《医学前沿(英文)》 2013年 第7卷 第2期 页码 270-273 doi: 10.1007/s11684-013-0261-7
In the presence of a large patent ductus arteriosus (PDA), aortic co-arctation (CoA) cannot be diagnosed clinically because PDA masks the clinical features. This condition impedes the identification of CoA by transthoracic echcocardiography. However, the closure of PDA can result in a severe clinical condition that causes a patient with undiagnosed CoA to suffer from shock and multi-organ failure. In this article, a case of PDA was presented, in which transesophageal echocardiography provided full information that could be used as reference to identify and define CoA during PDA ligation surgery.
关键词: patent ductus arteriosus aortic co-arctation transesophageal echocardiography
Enyuan TU MD, Yongjun PAN MM, Kang ZHENG MM, Zhaohua WANG MD, Qiansheng LIANG MD, Guangtian YANG MD,
《医学前沿(英文)》 2009年 第3卷 第4期 页码 431-436 doi: 10.1007/s11684-009-0088-4
关键词: tanshinone II A myocardial hypertrophy rat protein kinase B abdominal aorta coarctation
标题 作者 时间 类型 操作
Aortic aneurysm and chronic disseminated intravascular coagulation: a retrospective study of 235 patients
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期刊论文
engineering in the construction of numerical simulation oriented patient-specific model of stented aorticarch aneurysm
Xianlong MENG, Wenyu FU, Yun ZHANG, Aike QIAO,
期刊论文
Identification of variants associated with sporadic thoracic aortic dissection: a case--control study
期刊论文
Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience
null
期刊论文
Right coronary occlusion following transcatheter aortic valve implantation: two case reports
null
期刊论文
Clinical significance of para-aortic lymph node dissection and prognosis in ovarian cancer
null
期刊论文
in improving left ventricular remodelling and clinical outcome following surgical and trans-catheter aortic
期刊论文
Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation
SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei
期刊论文
Histopathological study of congenital aortic valve malformations in 32 children
HUANG Ping, WANG Hongwei, LI Yanping, CHENG Peixuan, LIU Qingjun, ZHANG Zhenlu, LIU Jianying
期刊论文
Effect of bradykinin on bradykinin-B2 receptor in rat aortic vascular smooth muscle cells and the involved
Wen YAN MD, Min FENG MD, Pei-Hua WANG MD, Dao-Wen WANG MD,
期刊论文
Unexpected co-arctation of aorta detected by transesophageal echocardiography during patent ductus arteriosus ligation
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期刊论文